Automatic Liquid Vial Filling Line:

Automatic Liquid Vial Filling Line: (Liquid Vial Compact Line)

Description

A Vial Compact Line is a fully integrated system for washing, sterilizing, filling, stoppering, and capping vials in a continuous process. Designed for pharmaceutical injectable production, it ensures aseptic processing under cGMP and FDA guidelines.

Where the Automatic Liquid Vial Filling Line fits in your production line

This compact line combines vial washing, depyrogenation, filling, stoppering and capping. Downstream, add an external vial washing machine, visual inspection and a vial sticker labeller. For separate machines, see vial washing machines and the liquid vial filling and stoppering machine.

Other models in this range

Need help choosing? Send your requirement with your container size, fill volume and output, or contact our team in Ahmedabad.

Automatic Liquid Vial Filling Line: (Liquid Vial Compact Line)

  • No vial – no fill, no stopper – no fill
  • Servo-driven indexing system
  • Online reject system for missing stoppers
  • Fully integrated vial washing, sterilizing, filling, stoppering, and capping in one line.
  • Laminar airflow with HEPA filtration ensures aseptic conditions.
  • High-speed, low-maintenance modular design.
  • Easy format changeover for multiple vial sizes.
  • Option for integration with inspection and labeling machines.
Bottle Unscrambler

Automatic Liquid Vial Filling Line: (Liquid Vial Compact Line) Technical Specification

Vial Washing Machine

Output Speed: Up to 300 vials/minute
Vial Sizes: 2 ml to 100 ml (ISO standard)
Washing Stations: 8 – 12 (internal & external)
Washing Media: WFI (Water for Injection), purified water, compressed air
Easy format part changeover
Construction: Contact parts in SS316L, frame in SS304

Vial Sterilizing Tunnel (Depyrogenation Tunnel)

Capacity: Matches washer output (300 VPM)
Heating Zone Temp: 250°C – 320°C (validated)
Cooling Zone: HEPA-filtered laminar airflow (ISO 5/Class 100)
Control: PLC-based, with temperature recording and alarm system
Construction: SS316L in product contact area, fully insulated

Vial Filling & Stoppering Machine

Output Speed: Up to 300 VPM
Filling Range: 2 ml to 100 ml
Filling Accuracy: ±0.5% (servo-driven piston or peristaltic pump)
No. of Filling Heads: 4 – 12 (as per speed requirement)
Stoppering Type: Full or partial rubber stoppering under Class 100 laminar airflow

Vial Capping Machine

Output Speed: Up to 300 VPM
Cap Size: 13mm, 20mm, 28mm (customizable)
Capping Type: Rotary pick-and-place or spinning roller type
No vial – no cap interlock
Consistent sealing torque
In-line reject for uncapped/mis-capped vials

Control & Compliance:

Automation: PLC with HMI touch screen
Data Recording: 21 CFR Part 11 (optional)
Validation Support: DQ, IQ, OQ, PQ documentation
Compliance: cGMP, GAMP 5 standards

Utilities Required:

Electrical Supply: 415V, 3 Phase, 50/60 Hz
Compressed Air: 6 bar, dry, oil-free
WFI Supply: Required for washing stations
Classified Area: ISO 5 (Class 100) at filling and stoppering zone