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Automatic Liquid Vial Filling Line:

Automatic Liquid Vial Filling Line: (Liquid Vial Compact Line)

Description

A Vial Compact Line is a fully integrated system for washing, sterilizing, filling, stoppering, and capping vials in a continuous process. Designed for pharmaceutical injectable production, it ensures aseptic processing under cGMP and FDA guidelines.

Automatic Liquid Vial Filling Line: (Liquid Vial Compact Line)

  • No vial – no fill, no stopper – no fill
  • Servo-driven indexing system
  • Online reject system for missing stoppers
  • Fully integrated vial washing, sterilizing, filling, stoppering, and capping in one line.
  • Laminar airflow with HEPA filtration ensures aseptic conditions.
  • High-speed, low-maintenance modular design.
  • Easy format changeover for multiple vial sizes.
  • Option for integration with inspection and labeling machines.
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Automatic Liquid Vial Filling Line: (Liquid Vial Compact Line) Technical Specification

Vial Washing Machine

Output Speed: Up to 300 vials/minute
Vial Sizes: 2 ml to 100 ml (ISO standard)
Washing Stations: 8 – 12 (internal & external)
Washing Media: WFI (Water for Injection), purified water, compressed air
Easy format part changeover
Construction: Contact parts in SS316L, frame in SS304

Vial Sterilizing Tunnel (Depyrogenation Tunnel)

Capacity: Matches washer output (300 VPM)
Heating Zone Temp: 250°C – 320°C (validated)
Cooling Zone: HEPA-filtered laminar airflow (ISO 5/Class 100)
Control: PLC-based, with temperature recording and alarm system
Construction: SS316L in product contact area, fully insulated
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Vial Filling & Stoppering Machine

Output Speed: Up to 300 VPM
Filling Range: 2 ml to 100 ml
Filling Accuracy: ±0.5% (servo-driven piston or peristaltic pump)
No. of Filling Heads: 4 – 12 (as per speed requirement)
Stoppering Type: Full or partial rubber stoppering under Class 100 laminar airflow

Vial Capping Machine

Output Speed: Up to 300 VPM
Cap Size: 13mm, 20mm, 28mm (customizable)
Capping Type: Rotary pick-and-place or spinning roller type
No vial – no cap interlock
Consistent sealing torque
In-line reject for uncapped/mis-capped vials

Control & Compliance:

Automation: PLC with HMI touch screen
Data Recording: 21 CFR Part 11 (optional)
Validation Support: DQ, IQ, OQ, PQ documentation
Compliance: cGMP, GAMP 5 standards

Utilities Required:

Electrical Supply: 415V, 3 Phase, 50/60 Hz
Compressed Air: 6 bar, dry, oil-free
WFI Supply: Required for washing stations
Classified Area: ISO 5 (Class 100) at filling and stoppering zone