Automatic Ampoule Filling Line:

Automatic Ampoule Filling Line: (Ampoule Compact Line)

An Ampoule Compact Line is a fully integrated production line for washing, sterilizing, filling, and sealing ampoules in a continuous operation. It handles 1 ml to 20 ml (ISO standard); delivers a production output of Up to 300 ampoules/minute; and is built to cGMP and FDA-approved material standards. Request a detailed specification sheet or a quote from Harsiddh Engineering.

Description

An Ampoule Compact Line is a fully integrated production line for washing, sterilizing, filling, and sealing ampoules in a continuous operation. It is designed for pharmaceutical and biotech industries to handle high-speed, aseptic ampoule production in compliance with cGMP and FDA standards.

Where the Automatic Ampoule Filling Line fits in your production line

This compact line combines ampoule washing, sterilizing, filling and sealing in one machine. Downstream, add visual ampoule inspection and an ampoule sticker labelling machine. If you need separate machines instead, see our ampoule washing machines and ampoule filling and sealing machines.

Other models in this range

Need help choosing? Send your requirement with your container size, fill volume and output, or contact our team in Ahmedabad.

Features of Automatic Ampoule Filling Line: (Ampoule Compact Line)

  • Compact footprint – integrated washer, sterilizer, filler, and sealer.
  • Designed for aseptic filling under laminar airflow.
  • High-speed, low-maintenance operation.
  • Optional automatic infeed/outfeed to packaging lines.
  • HEPA-filtered air handling for Class 100 (ISO 5) environment.
Bottle Unscrambler

Automatic Ampoule Filling Line: (Ampoule Compact Line) Technical Specification

Ampoule Washing Machine

Output Speed: Up to 300 ampoules/minute
Ampoule Sizes: 1 ml to 20 ml (ISO standard)
Washing Stations: 8 – 10 (internal & external washing)
Water Usage: WFI (Water for Injection) and compressed air washing
Construction: SS316L contact parts, SS304 frame

Ampoule Sterilizing Tunnel (Depyrogenation Tunnel)

Capacity: Matches washer output (300 APM)
Heating Zone Temperature: Up to 320°C (validated)
Cooling Zone: Laminar airflow with HEPA filters (H14)
Control: PLC with temperature profile recording
Construction: SS316L in product contact areas, fully insulated

Ampoule Filling & Sealing Machine

Output Speed: Up to 300 APM
Filling Range: 1 ml to 20 ml
Filling Accuracy: ±0.5%
No. of Filling Heads: 6 – 12 heads (rotary or linear)
Sealing Type: Flame sealing with LPG/oxygen mixture
Gas Usage: Optional inert gas flushing (before & after filling)
Servo-driven indexing system

Control & Compliance:

Automation: Fully PLC controlled with HMI interface
Data Recording: 21 CFR Part 11 compliance (optional)
Validation: DQ, IQ, OQ, PQ documentation support
Construction: cGMP compliant, easy-to-clean design

Utilities Required:

Electrical Supply: 415V, 3 Phase, 50Hz
Compressed Air: 6 bar dry, oil-free
WFI Supply: 2 – 3 bar pressure
Oxygen & LPG: For sealing burners

Frequently Asked Questions

What container sizes does the Automatic Ampoule Filling Line: (Ampoule Compact Line) handle?

Automatic Ampoule Filling Line: (Ampoule Compact Line)'s ampoule Sizes: is 1 ml to 20 ml (ISO standard).

What production output can I expect from the Automatic Ampoule Filling Line: (Ampoule Compact Line)?

Automatic Ampoule Filling Line: (Ampoule Compact Line)'s output Speed: is Up to 300 ampoules/minute.

What is the Washing Stations: of the Automatic Ampoule Filling Line: (Ampoule Compact Line)?

Automatic Ampoule Filling Line: (Ampoule Compact Line)'s washing Stations: is 8 – 10 (internal & external washing).

What is the Construction: of the Automatic Ampoule Filling Line: (Ampoule Compact Line)?

Automatic Ampoule Filling Line: (Ampoule Compact Line)'s construction: is SS316L contact parts, SS304 frame.

Is the Automatic Ampoule Filling Line: (Ampoule Compact Line) built to pharmaceutical industry standards?

Yes — it is built to cGMP and FDA-approved material standards.